| 2024-06 |
Immortalized nanodendritic cells decorated with immune-checkpoint inhibitors for personalized cancer immunotherapy |
Nano Today
|
| 2023-11 |
A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway |
Frontiers in Pharmacology
|
| 2023-11 |
Better understanding CD8+ T cells in cancer and viral infections |
Nature Immunology
|
| 2023-08 |
A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity |
Nature Immunology
|
| 2023-07 |
Discovery of highly immunogenic spleen-resident FCGR3+CD103+ cDC1s differentiated by IL-33-primed ST2+ basophils |
Cellular and Molecular Immunology
|
| 2023-05 |
Chronic LCMV infection regulates the effector T cell response by inducing the generation of less immunogenic dendritic cells |
Experimental & Molecular Medicine
|
| 2023-04 |
Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection |
Immune Network
|
| 2023-02 |
The oxidative phosphorylation inhibitor IM156 suppresses B-cell activation by regulating mitochondrial membrane potential and contributes to the mitigation of systemic lupus erythematosus |
Kidney International
|
| 2023-01 |
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells |
Nature Immunology
|
| 2022-12 |
Gut microbiota of the young ameliorates physical fitness of the aged in mice |
Microbiome
|
| 2022-11 |
Establishment of a mechanism-based in vitro coculture assay for evaluating the efficacy of immune checkpoint inhibitors |
Cancer Immunology, Immunotherapy
|
| 2022-09 |
Regulatory T cells in the tumour microenvironment of head and neck cancer: Emerging target in the era of immunotherapy |
Clinical and Translational Discovery
|
| 2022-06 |
Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx |
NATURE COMMUNICATIONS
|
| 2022-03 |
Disproportional enrichment of FoxP3(+)CD4(+) regulatory T cells shapes a suppressive tumourmicroenvironment in head and neck squamous cell carcinoma |
Clinical and translational medicine
|
| 2022-02 |
Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherapy |
Immune Network
|
| 2022-01 |
OASL1-Mediated Inhibition of Type I IFN Reduces Influenza A Infection-Induced Airway Inflammation by Regulating ILC2s |
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
|
| 2021-11 |
Differential Role of PD-1 Expressed by Various Immune and Tumor Cells in the Tumor Immune Microenvironment: Expression, Function, Therapeutic Efficacy, and Resistance to Cancer Immunotherapy |
Frontiers in Cell and Developmental Biology
|
| 2021-10 |
Engineered Attenuated Salmonella typhimurium Expressing Neoantigen Has Anticancer Effects |
ACS SYNTHETIC BIOLOGY
|
| 2021-10 |
Distinct exhaustion features of T lymphocytes shape the tumor-immune microenvironment with therapeutic implication in patients with non-small-cell lung cancer. |
Journal for ImmunoTherapy of Cancer
|
| 2021-10 |
Dysregulation of TFH-B-TRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer |
NATURE COMMUNICATIONS
|
| 2021-10 |
Therapeutic efficacy of cancer vaccine adjuvanted with nanoemulsion loaded with TLR7/8 agonist in lung cancer model |
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
|
| 2021-09 |
Overexpression of poliovirus receptor is associated with poor prognosis in head and neck squamous cell carcinoma patients |
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
|
| 2021-08 |
Perspectives on immune checkpoint ligands: expression, regulation, and clinical implications |
BMB REPORTS
|
| 2021-06 |
Enriching CCL3 in the Tumor Microenvironment Facilitates T cell Responses and Improves the Efficacy of Anti-PD-1 Therapy |
Immune Network
|
| 2021-05 |
Clinical Insights Into Novel Immune Checkpoint Inhibitors |
FRONTIERS IN PHARMACOLOGY
|
| 2021-05 |
Clinical Perspectives to Overcome Acquired Resistance to Anti-Programmed Death-1 and Anti-Programmed Death Ligand-1 therapy in Non-Small Cell Lung Cancer |
MOLECULES AND CELLS
|
| 2021-04 |
Programmed Death Ligand 1-Expressing Classical Dendritic Cells Mitigate Helicobacter-Induced Gastritis |
CMGH Cellular and Molecular Gastroenterology and Hepatology
|
| 2021-04 |
Overexpression of PVR and PD-L1 and its association with prognosis in surgically resected squamous cell lung carcinoma |
SCIENTIFIC REPORTS
|
| 2021-03 |
Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation |
JOURNAL OF EXPERIMENTAL MEDICINE
|
| 2021-02 |
Biosynthesis of Nonimmunosuppressive ProlylFK506 Analogues with Neurite Outgrowth and Synaptogenic Activity |
JOURNAL OF NATURAL PRODUCTS
|
| 2021-01 |
CU06-1004-Induced Vascular Normalization Improves Immunotherapy by Modulating Tumor Microenvironment via Cytotoxic T Cells |
FRONTIERS IN IMMUNOLOGY
|
| 2021-01 |
Systems biology analysis identifies TNFRSF9 as a functional marker of tumor-infiltrating regulatory T-cell enabling clinical outcome prediction in lung cancer |
Computational and Structural Biotechnology Journal
|
| 2020-11 |
Tumor-infiltrating regulatory T-cell accumulation in the tumor microenvironment is mediated by IL33/ST2 signaling |
CANCER IMMUNOLOGY RESEARCH
|
| 2020-09 |
Genome-wide identification of differentially methylated promoters and enhancers associated with response to anti-PD-1 therapy in non-small cell lung cancer |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2020-08 |
Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2020-07 |
Combination of PD-L1 and PVR determines sensitivity to PD-1 blockade |
JCI insight
|
| 2020-06 |
Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer |
SCIENTIFIC REPORTS
|
| 2020-02 |
Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer |
GENOME MEDICINE
|
| 2020-02 |
Re-defining T-Cell Exhaustion: Subset, Function, and Regulation |
Immune Network
|
| 2020-01 |
VirtualCytometry: a webserver for evaluating immune cell differentiation using single-cell RNA sequencing data |
BIOINFORMATICS
|
| 2019-12 |
Tumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function |
Journal for ImmunoTherapy of Cancer
|
| 2019-10 |
Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model |
SCIENTIFIC REPORTS
|
| 2019-08 |
Structural Study of Monomethyl Fumarate-Bound Human GAPDH |
MOLECULES AND CELLS
|
| 2019-08 |
Extrinsic Acquisition of CD80 by Antigen-Specific CD8+ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection |
Immune Network
|
| 2019-08 |
Monocyte-derived dendritic cells dictate the memory differentiation of CD8+ T cells during acute infection |
FRONTIERS IN IMMUNOLOGY
|
| 2019-08 |
Biosynthesis of nonimmunosuppressive FK506 analogues with antifungal activity |
JOURNAL OF NATURAL PRODUCTS
|
| 2019-07 |
CD160 serves as a negative regulator of NKT cells in acute hepatic injury |
NATURE COMMUNICATIONS
|
| 2019-04 |
Metabolic Reprogramming by the Excessive AMPK Activation Exacerbates Antigen-Specific Memory CD8+ T Cell Differentiation after Acute Lymphocytic Choriomeningitis Virus Infection |
Immune Network
|
| 2019-04 |
Sustained Type I Interferon Reinforces NK Cell-Mediated Cancer Immunosurveillance during Chronic Virus Infection |
CANCER IMMUNOLOGY RESEARCH
|
| 2019-03 |
The R229Q mutation of Rag2 does not characterize severe immunodeficiency in mice |
SCIENTIFIC REPORTS
|
| 2019-01 |
IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation |
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
|
| 2019-01 |
The Ratio of Peripheral Regulatory T Cells to Lox-11 Polymorphonuclear Myeloid-derived Suppressor Cells Predicts the Early Response to Anti–PD-1 Therapy in Patients with Non–Small Cell Lung Cancer |
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
|
| 2018-04 |
MicroRNA-150 controls differentiation of intraepithelial lymphocytes through TGF-beta receptor II regulation |
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
|
| 2018-02 |
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis |
NATURE COMMUNICATIONS
|
| 2017-10 |
Semi-Functional Quantitative Flow Cytometry Assay for Lymphocytic Choriomeningitis Virus Titration |
Immune Network
|
| 2017-09 |
miR-150-Mediated Foxo1 Regulation Programs CD8<sup>+</sup> T Cell Differentiation |
CELL REPORTS
|
| 2017-08 |
Concordance of programmed death-ligand 1 expression between primary and metastatic non-small cell lung cancer by immunohistochemistry and RNA in situ hybridization. |
ONCOTARGET
|
| 2017-08 |
Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus. |
ARTHRITIS RESEARCH & THERAPY
|
| 2017-07 |
TLR2 contributes to trigger immune response of pleural mesothelial cells against Mycobacterium bovis BCG and M. tuberculosis infection |
CYTOKINE
|
| 2017-06 |
MicroRNA-150 modulates intracellular Ca2+ levels in naive CD8+ T cells by targeting TMEM20 |
SCIENTIFIC REPORTS
|
| 2016-11 |
PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for head and neck cancer patients |
SCIENTIFIC REPORTS
|
| 2016-09 |
Combination of TLR1/2 and TLR3 ligands enhances CD4+ T cell longevity and antibody responses by modulating type I IFN production |
SCIENTIFIC REPORTS
|
| 2016-06 |
Phenotypic and functional analysis of activated regulatory T cells isolated from chronic lymphocytic choriomeningitis virus-infected mice |
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
|
| 2016-06 |
Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity |
ONCOTARGET
|
| 2016-05 |
Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells |
PLOS ONE
|
| 2016-04 |
Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues |
Immune Network
|
| 2016-04 |
Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments |
CANCER RESEARCH AND TREATMENT
|
| 2016-02 |
Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications |
Immune Network
|
| 2015-12 |
A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens |
SCIENTIFIC REPORTS
|
| 2015-11 |
AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation |
JOURNAL OF CELL BIOLOGY
|
| 2015-10 |
IL-4 Induced Innate CD8(+) T Cells Control Persistent Viral Infection |
PLOS PATHOGENS
|
| 2015-09 |
PD-1: Dual guard for immunopathology |
ONCOTARGET
|
| 2015-06 |
PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells |
JOURNAL OF IMMUNOLOGY
|
| 2015-02 |
Discrimination between active and latent tuberculosis based on the ratio of antigen-specific and mitogen-induced IP-10 production |
JOURNAL OF CLINICAL MICROBIOLOGY
|
| 2015-02 |
Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell?proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings |
JOURNAL OF LEUKOCYTE BIOLOGY
|
| 2015-01 |
Identification of a subnuclear body involved in sequence-specific cytokine RNA processing |
NATURE COMMUNICATIONS
|
| 2015-01 |
Diagnostic Performance of a Cytokine and IFN-γ Induced Chemokine mRNA Assay after Mycobacterium tuberculosis Specific Antigen Stimulation in Whole Blood from Infected Individuals |
JOURNAL OF MOLECULAR DIAGNOSTICS
|
| 2014-09 |
Inhibition of IL-17A Suppresses Enhanced-Tumor Growth in Low Dose Pre-Irradiated Tumor Beds |
PLOS ONE
|
| 2014-08 |
Enhancing T Cell Immune Responses by B Cell-based Therapeutic Vaccine Against Chronic Virus Infection |
Immune Network
|
| 2014-06 |
Regulatory T cells-an important target for cancer immunotherapy |
NATURE REVIEWS CLINICAL ONCOLOGY
|
| 2014-05 |
Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice |
ONCOTARGET
|
| 2014-01 |
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases |
GENOME RESEARCH
|
| 2014-01 |
Differentiation of Antigen-Specific T Cells with Limited Functional Capacity during Mycobacterium tuberculosis Infection |
INFECTION AND IMMUNITY
|
| 2013-09 |
Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity |
EUROPEAN JOURNAL OF IMMUNOLOGY
|