| 2023-07 |
Combination of the LARS1 Inhibitor, BC-LI-0186 with a MEK1/2 Inhibitor Enhances the Anti-Tumor Effect in Non-Small Cell Lung Cancer |
Cancer Research and Treatment
|
| 2023-06 |
Nutrient sensors and their crosstalk |
Experimental & Molecular Medicine
|
| 2023-03 |
Enhanced Glutaminolysis Drives Hypoxia-Induced Chemoresistance in Pancreatic Cancer |
Cancer Research
|
| 2022-12 |
O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine |
Nature Communications
|
| 2022-05 |
Functional and pathologic association of aminoacyl-tRNA synthetases with cancer |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2022-01 |
Amino Acid Metabolism in Cancer Drug Resistance |
Cells
|
| 2021-07 |
Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction |
BIOORGANIC CHEMISTRY
|
| 2021-04 |
Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation |
CELL REPORTS
|
| 2021-03 |
Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer |
EBioMedicine
|
| 2021-01 |
Aminoacyl-tRNA synthetases and amino acid signaling |
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
|
| 2020-09 |
Glutamine reliance in cell metabolism |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2020-02 |
A Variant of SLC1A5 is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells |
CELL METABOLISM
|
| 2020-01 |
Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1 |
SCIENCE
|
| 2019-06 |
Fluorescent 1,4-naphthoquinones to visualize diffuse and dense-core amyloid plaques in APP/PS1 transgenic mouse brains |
ACS CHEMICAL NEUROSCIENCE
|
| 2019-05 |
Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer |
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
|
| 2019-05 |
Glycoprotein 96 polymorphisms are associated with the risk of systemic lupus erythematosus: A case-control study |
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
|
| 2019-05 |
Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration |
JOURNAL OF CLINICAL INVESTIGATION
|
| 2018-08 |
The HDAC6 inhibitor ACY-1215 enhances the anticancer activity of oxaliplatin in colorectal cancer cells |
INTERNATIONAL JOURNAL OF ONCOLOGY
|
| 2018-06 |
Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2017-09 |
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction |
NATURE COMMUNICATIONS
|
| 2017-08 |
Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells |
ONCOGENE
|
| 2017-03 |
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia |
AMERICAN JOURNAL OF HUMAN GENETICS
|
| 2017-03 |
A human antibody that binds to the sixth Ig-like domain of VCAM-1 blocks lung cancer cell migration in vitro |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
|
| 2016-08 |
Leucyl-tRNA synthetase activates Vps34 in amino acid-sensing mTORC1 signaling |
CELL REPORTS
|
| 2016-08 |
AIMP2 controls intestinal stem cell compartments and tumorigenesis by modulating Wnt/b-catenin signaling |
CANCER RESEARCH
|
| 2016-06 |
Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2 |
CANCER RESEARCH
|
| 2015-12 |
Direct Regulation of TLR5 Expression by Caveolin-1 |
MOLECULES AND CELLS
|
| 2015-10 |
Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence |
AGING CELL
|
| 2015-01 |
AIMP1 negatively regulates PPARgamma: Implication in adipogenesis |
Receptors & Clinical Investigation
|
| 2014-10 |
AIMP1 negatively regulates adipogenesis by inhibiting PPARγ |
JOURNAL OF CELL SCIENCE
|
| 2014-01 |
Protein-protein interactions and multi-component complexes of aminoacyl-tRNA synthetases |
TOPICS IN CURRENT CHEMISTRY
|
| 2014-01 |
Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction |
NATURE CHEMICAL BIOLOGY
|
| 2013-09 |
Chemical suppression of an oncogenic splicing variant of AIMP2 induces tumour regression |
BIOCHEMICAL JOURNAL
|